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Sin Nombre virus : ウィキペディア英語版 | Sin Nombre virus
The Sin Nombre virus (SNV) (from the Spanish meaning "the nameless virus") is the prototypical etiologic agent of hantavirus cardiopulmonary syndrome (HCPS). Its original name was "Four Corners virus." The name was changed after local residents raised objections. ==History== It was first isolated in 1993 from rodents collected near the home of one of the initial patients with hantavirus pulmonary syndrome (HPS) in the Four Corners region of the western United States. Isolation was achieved through blind passage in ''Peromyscus maniculatus'' (deer mouse) and subsequent adaptation to growth in Vero E6 cells. Additional viral strains have also been isolated from ''P. maniculatus'' associated with a fatal case in California and ''P. leucopus'' from the vicinity of probable infection of a New York case. Black Creek Canal virus was isolated from ''S. hispidus'' collected near the residence of a human case in Dade County, Florida. Another etiologic agent of HCPS, Bayou virus, was first isolated from the vicinity of Monroe, Louisiana.
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